Computational Biophysical Chemistry

Hansmann Group







Contact us at:
Dept. of Chemistry and Biochemistry
University of Oklahoma
101 Stephenson Parkway
Norman, OK 73019-5251,USA


E-mail: uhansmann at ou.edu
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Ping Jiang

Position

Postdoctoral Associate

Address

Stephenson Life Sciences Research Center 3000,
101 Stephenson Parkway, Norman, OK 73019-5251, USA

Phone

(+1)405-265-8882

E-mail

pingj at ou.edu




EDUCATION & EMPLOYMENT

2002-2006, Bachelor's degree, Shandong University, China

2007-2011, PhD degree, Nanyang Technological University, Singapore

Sep 2011-, Post Doctoral Researcher, University of Oklahoma, US

RESEARCH INTERESTS

Simulation and modeling of biological molecules

PUBLICATIONS

Jiang, P., Li, W., Shea, J.-E. & Mu, Y.,
"Resveratrol inhibits the formation of multiple-layered β-sheet oligomers of the human islet amyloid polypeptide segment 22-27.",
Biophysical J. , 100 , 1550-1558 (2011)

Jiang, P., Wei, L., Pervushin, K. & Mu, Y.,
"pH-Dependent interactions of human islet amyloid polypeptide segments with insulin studied by replica exchange molecular dynamics simulations",
J. Phys. Chem. B.,114, 10176-83 (2010)

Jiang, P., Xu, W. & Mu, Y.,
"Amyloidogenesis abolished by proline substitutions but enhanced by lipid binding.",
PLoS Comput Biol,5 , e1000357 (2009)

Wei, L., Jiang, P., Xu, W., Li, H., Zhang, H., Yan, L., Chan-Park, M. B., Liu, X. W., Tang, K., Mu, Y. & Pervushin, K.,
"The molecular basis of distinct aggregation pathways of islet amyloid polypeptide.",
J. Biol. Chem., 286 , 6291-6300 (2011)

Wei, L., Jiang, P., Yau, Y. H., Summer, H., Shochat, S. G., Mu, Y. & Pervushin, K.,
"Residual structure in islet amyloid polypeptide mediates its interactions with soluble insulin.",
Biochemistry, 48 , 2368-76 (2009)

Xu, W., Jiang, P. & Mu, Y.,
"Conformation preorganization: effects of S20G mutation on the structure of human islet amyloid polypeptide segment.",
J Phys Chem B, 113, 7308-14 (2009)

Xu, W., Jiang, P., Li, W. & Mu, Y.,
"Assembly dynamics of two-beta sheets revealed by molecular dynamics simulations.",
J Chem Phys, 130, 164709 (2009)

Wu, B., Jiang, P., Mu, Y. & Wilmouth, R. C.
"Cancer Osaka thyroid (Cot) phosphorylates Polo-like kinase (PLK1) at Ser137 but not at Thr210.",
Biol Chem,390, 1271-7 (2009)

Bai, Y., Liu, S., Jiang, P., Zhou, L., Li, J., Tang, C., Verma, C., Mu, Y., Beuerman, R. W. & Pervushin, K.,
"Structure-dependent charge density as a determinant of antimicrobial activity of peptide analogues of defensin.",
Biochemistry,48, 7229-39 (2009)